RNA Details
Disease Name
cardiomegaly
Tissue
heart
RNA Symbol
mir-133a-1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
PCR; CHIP etc.
Target
NA
Pathway
NA
PubMed ID
Title
HDACs Regulate miR-133a Expression in Pressure Overload Induced Cardiac Fibrosis
Year
2015
Function
"HDAC inhibition prevented this significant decrease 2 weeks post tac and maintained miR-133a expression,and the study revealed that a decrease in connective tissue growth factor expression,a reduction in cardiac fibrosis and left atrium diameter."
RNA Details
Disease Name
cardiomegaly
Tissue
heart
RNA Symbol
mir-133a-1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
PCR; CHIP etc.
Target
NA
Pathway
NA
PubMed ID
Title
HDACs Regulate miR-133a Expression in Pressure Overload Induced Cardiac Fibrosis
Year
2015
Function
"HDAC inhibition prevented this significant decrease 2 weeks post tac and maintained miR-134a expression,and the study revealed that a decrease in connective tissue growth factor expression,a reduction in cardiac fibrosis and left atrium diameter."